The Utilization of Marginal Donors for Cardiac Re-Transplantation

PurposeThe global shortage of available donor organs and the poor clinical outcomes re-transplant patients raise ethical economic concerns. In this study, we examined difference in post-transplant survival (re-HTx) with without use marginal hearts.MethodsThe United Network Organ Sharing database was retrospectively queried from January 2000 to March 2020 identify adult (17 > years) underwent re-HTx. Recipients were divided into early (≦6 months after previous transplant)and late (>6 transplant) groups based on timing re-transplantation. Demographic data compared donors each group. Marginal those who met at least one following characteristics: age greater than 55 years, cocaine or other intravenous drug use, hepatitis C positive, ejection fraction less 0.45, donor: recipient weight 0.8.ResultsThere 111 1133 re-transplantation.10-year mortality significantly higher transplantation (Early 61.0% vs. Late 44.9%, log-rank P<0.001). There no preoperative patient background between non-Marginal transplant group, while group had a BMI (p<0.001), PRA (p=0.005), longer total waiting time (0.018) non-marginal significant 10-year either groups. (Early: non-MD 58.5% MD 62.0%, P=0.827; Late: 43.2% 46.6%, P=0.699).ConclusionUtilization undergoing re-HTx is not associated worse both for graft failure. The hearts. 0.8. P=0.699). Utilization